205 East 45th Street, New York, NY 10017 | Tel 212-867-5100 | Reservations 800-428-1932
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Welcome to Wyndham Midtown 45: Manhattan Hotel Style with Residential Appeal

The Wyndham Midtown 45 is a serene, sophisticated oasis in the heart of midtown Manhattan. Located in Midtown Manhattan East, Wyndham Midtown 45 offers 199 hotel rooms and suites—including  studio, one bedroom and two bedroom suites and state-of-the-art amenities throughout. Wyndham Midtown 45 is the perfect choice for pleasure, business, or meetings and events.

33rd Floor Sky Lounge

Enjoy spectacular views from the 33rd Floor Sky Lounge, featuring indoor and outdoor seating and exciting events to participate in. Open daily from 7AM- 11PM.

Midtown Manhattan Hotel Location in the Center of the Action

Located in midtown Manhattan on 45th Street between 2nd and 3rd Avenues, Wyndham Midtown 45 is within walking distance of many of New York City’s major attractions and business centers. Here is a brief sampling of all of the key attractions located just steps from Wyndham Midtown 45’s front door.

  • Grand Central Station: Just blocks from this historic station
  • United Nations: Two blocks from the headquarters of the United Nations
  • Murray Hill
  • Park Avenue restaurants
  • Fifth Avenue shopping
  • Madison Avenue
  • Times Square
  • Theater District: From Broadway Hits to Rockette Kicks
  • SoHo
  • Tribeca
  • Wall Street

Public transportation is just around the corner, valet parking is available for guests arriving in their own cars, and private transportation is available upon request. Wyndham Midtown 45 is 12 miles from LaGuardia Airport and 17 miles from JFK International Airport. 

Midtown Manhattan East Accommodations

Our superior hotel amenities include:

  • Complimentary Wi-Fi Internet in all guest rooms, suites and public areas of the hotel
  • Limestone bathrooms with rain showers
  • Fully equipped fitness center
  • Flat panel televisions in every living room, bedroom, and bath. 
  • Suites all come fully equipped deluxe Poggen Pohl kitchens featuring stainless steel refrigerator, Advantium oven, Gaggenau cook top, Cuisinart coffee machine, and toaster.