205 East 45th Street, New York, NY 10017 | Tel 212-867-5100 | Reservations 800-428-1932
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Welcome to Wyndham Midtown 45: Manhattan Luxury Hotel Style with Residential Appeal

The Wyndham Midtown 45 is a serene, sophisticated oasis in the heart of midtown Manhattan. Located in Midtown Manhattan East, Wyndham Midtown 45 offers 199 luxury hotel rooms and suites—including  studio, one bedroom and two bedroom suites and state-of-the-art amenities throughout. Wyndham Midtown 45 is the perfect choice for pleasure, business, or meetings and events.

Resort Alert

Good enough isn't good enough for us! We've heard your feedback and are working to create a better resort for your future visits. After successfully completing renovations to 14 guestroom floors, the fitness center and the breathtaking 33rd Floor Sky Lounge, we will continue renovations to the lobby beginning mid-February 2016 with an anticipated completion in mid-July 2016. Guestroom renovations happen floor by floor, so we guarantee you will not be accommodated on a floor undergoing renovation. We appreciate your patience and continued support.

33rd Floor Sky Lounge

Enjoy spectacular views from the 33rd Floor Sky Lounge, featuring indoor and outdoor seating and exciting events to participate in. Open daily from 7AM- 11PM.

Midtown Manhattan Hotel Location in the Center of the Action

Located in midtown Manhattan on 45th Street between 2nd and 3rd Avenues, Wyndham Midtown 45 is within walking distance of many of New York City’s major attractions and business centers. Here is a brief sampling of all of the key attractions located just steps from Wyndham Midtown 45’s front door.

  • Grand Central Station: Just blocks from this historic station
  • United Nations: Two blocks from the headquarters of the United Nations
  • Murray Hill
  • Park Avenue restaurants
  • Fifth Avenue shopping
  • Madison Avenue
  • Times Square
  • Theater District: From Broadway Hits to Rockette Kicks
  • SoHo
  • Tribeca
  • Wall Street

Public transportation is just around the corner, valet parking is available for guests arriving in their own cars, and private transportation is available upon request. Wyndham Midtown 45 is 12 miles from LaGuardia Airport and 17 miles from JFK International Airport. 

Midtown Manhattan East Luxury Accommodations

Our superior hotel amenities include:

  • Complimentary Wi-Fi Internet in all guest rooms, suites and public areas of the hotel
  • Limestone bathrooms with rain showers
  • Fully equipped fitness center
  • Flat panel televisions in every living room, bedroom, and bath. 
  • Luxury suites all come fully equipped deluxe Poggen Pohl kitchens featuring stainless steel refrigerator, Advantium oven, Gaggenau cook top, Cuisinart coffee machine, and toaster.