205 East 45th Street, New York, NY 10017 | Tel 212-867-5100 | Reservations 866-701-8508
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Welcome to Wyndham Midtown 45: Manhattan Luxury Hotel Style with Residential Appeal

The Wyndham Midtown 45 is a serene, sophisticated oasis in the heart of midtown Manhattan. Located in Midtown Manhattan East, Wyndham Midtown 45 offers 203 luxury hotel rooms and suites—including  studio, one bedroom and two bedroom suites, all designed by residential architect Costas Kondylis, with custom designed furniture by David Rockwell and state-of-the-art amenities throughout. Wyndham Midtown 45 is the perfect choice for pleasure, business, or meetings and events.

Midtown Manhattan Hotel Location in the Center of the Action

Located in midtown Manhattan on 45th Street between 2nd and 3rd Avenues, Wyndham Midtown 45 is within walking distance of many of New York City’s major attractions and business centers. Here is a brief sampling of all of the key attractions located just steps from Wyndham Midtown 45’s front door.

  • Grand Central Station: Just blocks from this historic station
  • United Nations: Two blocks from the headquarters of the United Nations
  • Murray Hill
  • Park Avenue restaurants
  • Fifth Avenue shopping
  • Madison Avenue
  • Times Square
  • Theater District: From Broadway Hits to Rockette Kicks
  • SoHo
  • Tribeca
  • Wall Street

Public transportation is just around the corner, valet parking is available for guests arriving in their own cars, and private transportation is available upon request. Wyndham Midtown 45 is 12 miles from LaGuardia Airport and 17 miles from JFK International Airport. 

Midtown Manhattan East Luxury Accommodations

Perfect for guests looking for a memorable overnight, or those needing accommodations for an extended stay in New York City, our hotel is recognized as a four star hotel with first class amenities.
Experience for yourself the kind of luxury and convenience normally reserved for power executives, famous celebrities and dignitaries.

Our superior hotel amenities include:

  • Custom furnishings by renowned designer David Rockwell
  • Wifi Internet in all guest rooms, suites and public areas of the hotel
  • Limestone bathrooms with rain showers
  • Fully equipped fitness center
  • Flat panel televisions in every living room, bedroom, and bath. 
  • Luxury suites all come fully equipped deluxe Poggen Pohl kitchens featuring SubZero refrigerator, Advantium oven, and Gaggenau cook tops. 
  • Amazing views of New York Skyline from our Penthouse Suite

Stay for a night or for an extended stay –we’ll welcome you to our midtown Manhattan New York City hotel. Be sure to inquire about our extended stay weekly and monthly rates for great savings and a comparable step up from the usual residential suites and corporate rentals in New York City.